Publikationen

Publikationen seit 2020

H Skladny 2022: 0 / 2021: 1 / 2019: 0
1: Szot JO, Slavotinek A, Chong K, Brandau O, Nezarati M, Cueto-González AM,
Patel MS, Devine WP, Rego S, Acyinena AP, Shannon P, Myles-Reid D, Blaser S,
Mieghem TV, Yavuz-Kienle H, Skladny H, Miller K, Riera MDT, Martínez SA, Tizzano
EF, Dupuis L, James Stavropoulos D, McNiven V, Mendoza-Londono R, Elliott AM;
CAUSES Study, Phillips RS, Chapman G, Dunwoodie SL. New cases that expand the
genotypic and phenotypic spectrum of Congenital NAD Deficiency Disorder. Hum
Mutat. 2021 Jul;42(7):862-876. doi: 10.1002/humu.24211. Epub 2021 May 16. PMID:
33942433; PMCID: PMC8238843.

S Schwab 2022 0 2021 1 2019 0
1: Fath F, Bengeser A, Barresi M, Binner P, Schwab S, Ray KK, Krämer BK, Fraass
U, März W. FH ALERT: efficacy of a novel approach to identify patients with
familial hypercholesterolemia. Sci Rep. 2021 Oct 14;11(1):20421. doi:
10.1038/s41598-021-99961-y. PMID: 34650182; PMCID: PMC8516913.

R Klaes 2022 0 2021 0 2020 1
1: Cöktü S, Spix C, Kaiser M, Beygo J, Kleinle S, Bachmann N, Kohlschmidt N,
Prawitt D, Beckmann A, Klaes R, Nevinny-Stickel-Hinzpeter C, Döhnert S, Kraus C,
Kadgien G, Vater I, Biskup S, Kutsche M, Kohlhase J, Eggermann T, Zenker M,
Kratz CP. Cancer incidence and spectrum among children with genetically
confirmed Beckwith-Wiedemann spectrum in Germany: a retrospective cohort study.
Br J Cancer. 2020 Aug;123(4):619-623. doi: 10.1038/s41416-020-0911-x. Epub 2020
May 26. PMID: 32451468; PMCID: PMC7434760.

F Cremer 2022 0 2021 1 2020 2
1: Rippinger N, Fischer C, Sinn HP, Dikow N, Sutter C, Rhiem K, Grill S, Cremer
FW, Nguyen HP, Ditsch N, Kast K, Hettmer S, Kratz CP, Schott S. Breast cancer
characteristics and surgery among women with Li-Fraumeni syndrome in Germany-A
retrospective cohort study. Cancer Med. 2021 Nov;10(21):7747-7758. doi:
10.1002/cam4.4300. Epub 2021 Sep 26. PMID: 34569185; PMCID: PMC8559485.
2: Karremann M, Neumaier-Probst E, Schlichtenbrede F, Beier F, Brümmendorf TH,
Cremer FW, Bader P, Dürken M. Revesz syndrome revisited. Orphanet J Rare Dis.
2020 Oct 23;15(1):299. doi: 10.1186/s13023-020-01553-y. PMID: 33097095; PMCID:
PMC7583287.
3: Rippinger N, Fischer C, Haun MW, Rhiem K, Grill S, Kiechle M, Cremer FW, Kast
K, Nguyen HP, Ditsch N, Kratz CP, Vogel J, Speiser D, Hettmer S, Glimm H,
Fröhling S, Jäger D, Seitz S, Hahne A, Maatouk I, Sutter C, Schmutzler RK, Dikow
N, Schott S. Cancer surveillance and distress among adult pathogenic TP53
germline variant carriers in Germany: A multicenter feasibility and acceptance
survey. Cancer. 2020 Sep 1;126(17):4032-4041. doi: 10.1002/cncr.33004. Epub 2020
Jun 18. PMID: 32557628.

O Brandau: 2022 0 2021 1 2019 1
1: Szot JO, Slavotinek A, Chong K, Brandau O, Nezarati M, Cueto-González AM,
Patel MS, Devine WP, Rego S, Acyinena AP, Shannon P, Myles-Reid D, Blaser S,
Mieghem TV, Yavuz-Kienle H, Skladny H, Miller K, Riera MDT, Martínez SA, Tizzano
EF, Dupuis L, James Stavropoulos D, McNiven V, Mendoza-Londono R, Elliott AM;
CAUSES Study, Phillips RS, Chapman G, Dunwoodie SL. New cases that expand the
genotypic and phenotypic spectrum of Congenital NAD Deficiency Disorder. Hum
Mutat. 2021 Jul;42(7):862-876. doi: 10.1002/humu.24211. Epub 2021 May 16. PMID:
33942433; PMCID: PMC8238843.
2: Al-Kindi A, Al-Shehhi M, Westenberger A, Beetz C, Scott P, Brandau O, Abbasi-
Moheb L, Yüksel Z, Bauer P, Rolfs A, Grüning NM. A novel POC1A variant in an
alternatively spliced exon causes classic SOFT syndrome: clinical presentation
of seven patients. J Hum Genet. 2020 Jan;65(2):193-197. doi:
10.1038/s10038-019-0693-2. Epub 2019 Nov 26. PMID: 31767933.
ME Kleber:2022:19, 2021 19, 2020 15

2022
1: Yazdani B, Delgado GE, Kleber ME, Yücel G, Husain-Syed F, Kraemer TD, Jochims
J, Leipe J, März W, Krämer BK. The renin-angiotensin-aldosterone system,
neurohumoral axis and cardiovascular mortality in LURIC. J Clin Hypertens
(Greenwich). 2022 Dec;24(12):1587-1597. doi: 10.1111/jch.14593. Epub 2022 Nov 9.
PMID: 36349861; PMCID: PMC9731599.

2: Yengo L, Vedantam S, Marouli E, Sidorenko J, Bartell E, Sakaue S, Graff M,
Eliasen AU, Jiang Y, Raghavan S, Miao J, Arias JD, Graham SE, Mukamel RE,
Spracklen CN, Yin X, Chen SH, Ferreira T, Highland HH, Ji Y, Karaderi T, Lin K,
Lüll K, Malden DE, Medina-Gomez C, Machado M, Moore A, Rüeger S, Sim X, Vrieze
S, Ahluwalia TS, Akiyama M, Allison MA, Alvarez M, Andersen MK, Ani A, Appadurai
V, Arbeeva L, Bhaskar S, Bielak LF, Bollepalli S, Bonnycastle LL, Bork-Jensen J,
Bradfield JP, Bradford Y, Braund PS, Brody JA, Burgdorf KS, Cade BE, Cai H, Cai
Q, Campbell A, Cañadas-Garre M, Catamo E, Chai JF, Chai X, Chang LC, Chang YC,
Chen CH, Chesi A, Choi SH, Chung RH, Cocca M, Concas MP, Couture C, Cuellar-
Partida G, Danning R, Daw EW, Degenhard F, Delgado GE, Delitala A, Demirkan A,
Deng X, Devineni P, Dietl A, Dimitriou M, Dimitrov L, Dorajoo R, Ekici AB,
Engmann JE, Fairhurst-Hunter Z, Farmaki AE, Faul JD, Fernandez-Lopez JC, Forer
L, Francescatto M, Freitag-Wolf S, Fuchsberger C, Galesloot TE, Gao Y, Gao Z,
Geller F, Giannakopoulou O, Giulianini F, Gjesing AP, Goel A, Gordon SD, Gorski
M, Grove J, Guo X, Gustafsson S, Haessler J, Hansen TF, Havulinna AS, Haworth
SJ, He J, Heard-Costa N, Hebbar P, Hindy G, Ho YA, Hofer E, Holliday E, Horn K,
Hornsby WE, Hottenga JJ, Huang H, Huang J, Huerta-Chagoya A, Huffman JE, Hung
YJ, Huo S, Hwang MY, Iha H, Ikeda DD, Isono M, Jackson AU, Jäger S, Jansen IE,
Johansson I, Jonas JB, Jonsson A, Jørgensen T, Kalafati IP, Kanai M, Kanoni S,
Kårhus LL, Kasturiratne A, Katsuya T, Kawaguchi T, Kember RL, Kentistou KA, Kim
HN, Kim YJ, Kleber ME, Knol MJ, Kurbasic A, Lauzon M, Le P, Lea R, Lee JY,
Leonard HL, Li SA, Li X, Li X, Liang J, Lin H, Lin SY, Liu J, Liu X, Lo KS, Long
J, Lores-Motta L, Luan J, Lyssenko V, Lyytikäinen LP, Mahajan A, Mamakou V,
Mangino M, Manichaikul A, Marten J, Mattheisen M, Mavarani L, McDaid AF,
Meidtner K, Melendez TL, Mercader JM, Milaneschi Y, Miller JE, Millwood IY,
Mishra PP, Mitchell RE, Møllehave LT, Morgan A, Mucha S, Munz M, Nakatochi M,
Nelson CP, Nethander M, Nho CW, Nielsen AA, Nolte IM, Nongmaithem SS, Noordam R,
Ntalla I, Nutile T, Pandit A, Christofidou P, Pärna K, Pauper M, Petersen ERB,
Petersen LV, Pitkänen N, Polašek O, Poveda A, Preuss MH, Pyarajan S, Raffield
LM, Rakugi H, Ramirez J, Rasheed A, Raven D, Rayner NW, Riveros C, Rohde R,
Ruggiero D, Ruotsalainen SE, Ryan KA, Sabater-Lleal M, Saxena R, Scholz M,
Sendamarai A, Shen B, Shi J, Shin JH, Sidore C, Sitlani CM, Slieker RC, Smit
RAJ, Smith AV, Smith JA, Smyth LJ, Southam L, Steinthorsdottir V, Sun L,
Takeuchi F, Tallapragada DSP, Taylor KD, Tayo BO, Tcheandjieu C, Terzikhan N,
Tesolin P, Teumer A, Theusch E, Thompson DJ, Thorleifsson G, Timmers PRHJ,
Trompet S, Turman C, Vaccargiu S, van der Laan SW, van der Most PJ, van Klinken
JB, van Setten J, Verma SS, Verweij N, Veturi Y, Wang CA, Wang C, Wang L, Wang
Z, Warren HR, Bin Wei W, Wickremasinghe AR, Wielscher M, Wiggins KL, Winsvold
BS, Wong A, Wu Y, Wuttke M, Xia R, Xie T, Yamamoto K, Yang J, Yao J, Young H,
Yousri NA, Yu L, Zeng L, Zhang W, Zhang X, Zhao JH, Zhao W, Zhou W, Zimmermann
ME, Zoledziewska M, Adair LS, Adams HHH, Aguilar-Salinas CA, Al-Mulla F, Arnett
DK, Asselbergs FW, Åsvold BO, Attia J, Banas B, Bandinelli S, Bennett DA,
Bergler T, Bharadwaj D, Biino G, Bisgaard H, Boerwinkle E, Böger CA, Bønnelykke
K, Boomsma DI, Børglum AD, Borja JB, Bouchard C, Bowden DW, Brandslund I,
Brumpton B, Buring JE, Caulfield MJ, Chambers JC, Chandak GR, Chanock SJ,
Chaturvedi N, Chen YI, Chen Z, Cheng CY, Christophersen IE, Ciullo M, Cole JW,
Collins FS, Cooper RS, Cruz M, Cucca F, Cupples LA, Cutler MJ, Damrauer SM,
Dantoft TM, de Borst GJ, de Groot LCPGM, De Jager PL, de Kleijn DPV, Janaka de
Silva H, Dedoussis GV, den Hollander AI, Du S, Easton DF, Elders PJM, Eliassen
AH, Ellinor PT, Elmståhl S, Erdmann J, Evans MK, Fatkin D, Feenstra B, Feitosa
MF, Ferrucci L, Ford I, Fornage M, Franke A, Franks PW, Freedman BI, Gasparini
P, Gieger C, Girotto G, Goddard ME, Golightly YM, Gonzalez-Villalpando C,
Gordon-Larsen P, Grallert H, Grant SFA, Grarup N, Griffiths L, Gudnason V,
Haiman C, Hakonarson H, Hansen T, Hartman CA, Hattersley AT, Hayward C, Heckbert
SR, Heng CK, Hengstenberg C, Hewitt AW, Hishigaki H, Hoyng CB, Huang PL, Huang
W, Hunt SC, Hveem K, Hyppönen E, Iacono WG, Ichihara S, Ikram MA, Isasi CR,
Jackson RD, Jarvelin MR, Jin ZB, Jöckel KH, Joshi PK, Jousilahti P, Jukema JW,
Kähönen M, Kamatani Y, Kang KD, Kaprio J, Kardia SLR, Karpe F, Kato N, Kee F,
Kessler T, Khera AV, Khor CC, Kiemeney LALM, Kim BJ, Kim EK, Kim HL, Kirchhof P,
Kivimaki M, Koh WP, Koistinen HA, Kolovou GD, Kooner JS, Kooperberg C, Köttgen
A, Kovacs P, Kraaijeveld A, Kraft P, Krauss RM, Kumari M, Kutalik Z, Laakso M,
Lange LA, Langenberg C, Launer LJ, Le Marchand L, Lee H, Lee NR, Lehtimäki T, Li
H, Li L, Lieb W, Lin X, Lind L, Linneberg A, Liu CT, Liu J, Loeffler M, London
B, Lubitz SA, Lye SJ, Mackey DA, Mägi R, Magnusson PKE, Marcus GM, Vidal PM,
Martin NG, März W, Matsuda F, McGarrah RW, McGue M, McKnight AJ, Medland SE,
Mellström D, Metspalu A, Mitchell BD, Mitchell P, Mook-Kanamori DO, Morris AD,
Mucci LA, Munroe PB, Nalls MA, Nazarian S, Nelson AE, Neville MJ, Newton-Cheh C,
Nielsen CS, Nöthen MM, Ohlsson C, Oldehinkel AJ, Orozco L, Pahkala K, Pajukanta
P, Palmer CNA, Parra EJ, Pattaro C, Pedersen O, Pennell CE, Penninx BWJH,
Perusse L, Peters A, Peyser PA, Porteous DJ, Posthuma D, Power C, Pramstaller
PP, Province MA, Qi Q, Qu J, Rader DJ, Raitakari OT, Ralhan S, Rallidis LS, Rao
DC, Redline S, Reilly DF, Reiner AP, Rhee SY, Ridker PM, Rienstra M, Ripatti S,
Ritchie MD, Roden DM, Rosendaal FR, Rotter JI, Rudan I, Rutters F, Sabanayagam
C, Saleheen D, Salomaa V, Samani NJ, Sanghera DK, Sattar N, Schmidt B, Schmidt
H, Schmidt R, Schulze MB, Schunkert H, Scott LJ, Scott RJ, Sever P, Shiroma EJ,
Shoemaker MB, Shu XO, Simonsick EM, Sims M, Singh JR, Singleton AB, Sinner MF,
Smith JG, Snieder H, Spector TD, Stampfer MJ, Stark KJ, Strachan DP, 't Hart LM,
Tabara Y, Tang H, Tardif JC, Thanaraj TA, Timpson NJ, Tönjes A, Tremblay A,
Tuomi T, Tuomilehto J, Tusié-Luna MT, Uitterlinden AG, van Dam RM, van der Harst
P, Van der Velde N, van Duijn CM, van Schoor NM, Vitart V, Völker U,
Vollenweider P, Völzke H, Wacher-Rodarte NH, Walker M, Wang YX, Wareham NJ,
Watanabe RM, Watkins H, Weir DR, Werge TM, Widen E, Wilkens LR, Willemsen G,
Willett WC, Wilson JF, Wong TY, Woo JT, Wright AF, Wu JY, Xu H, Yajnik CS,
Yokota M, Yuan JM, Zeggini E, Zemel BS, Zheng W, Zhu X, Zmuda JM, Zonderman AB,
Zwart JA; 23andMe Research Team; VA Million Veteran Program; DiscovEHR
(DiscovEHR and MyCode Community Health Initiative); eMERGE (Electronic Medical
Records and Genomics Network); Lifelines Cohort Study; PRACTICAL Consortium;
Understanding Society Scientific Group, Chasman DI, Cho YS, Heid IM, McCarthy
MI, Ng MCY, O'Donnell CJ, Rivadeneira F, Thorsteinsdottir U, Sun YV, Tai ES,
Boehnke M, Deloukas P, Justice AE, Lindgren CM, Loos RJF, Mohlke KL, North KE,
Stefansson K, Walters RG, Winkler TW, Young KL, Loh PR, Yang J, Esko T, Assimes
TL, Auton A, Abecasis GR, Willer CJ, Locke AE, Berndt SI, Lettre G, Frayling TM,
Okada Y, Wood AR, Visscher PM, Hirschhorn JN. A saturated map of common genetic
variants associated with human height. Nature. 2022 Oct;610(7933):704-712. doi:
10.1038/s41586-022-05275-y. Epub 2022 Oct 12. PMID: 36224396; PMCID: PMC9605867.

3: Marttila S, Tamminen H, Rajić S, Mishra PP, Lehtimäki T, Raitakari O, Kähönen
M, Kananen L, Jylhävä J, Hägg S, Delerue T, Peters A, Waldenberger M, Kleber ME,
März W, Luoto R, Raitanen J, Sillanpää E, Laakkonen EK, Heikkinen A, Ollikainen
M, Raitoharju E. Methylation status of <i>VTRNA2-1</i>/<i>nc886</i> is stable
across populations, monozygotic twin pairs and in majority of tissues.
Epigenomics. 2022 Sep;14(18):1105-1124. doi: 10.2217/epi-2022-0228. Epub 2022
Oct 5. PMID: 36200237.

4: Ramdas S, Judd J, Graham SE, Kanoni S, Wang Y, Surakka I, Wenz B, Clarke SL,
Chesi A, Wells A, Bhatti KF, Vedantam S, Winkler TW, Locke AE, Marouli E, Zajac
GJM, Wu KH, Ntalla I, Hui Q, Klarin D, Hilliard AT, Wang Z, Xue C, Thorleifsson
G, Helgadottir A, Gudbjartsson DF, Holm H, Olafsson I, Hwang MY, Han S, Akiyama
M, Sakaue S, Terao C, Kanai M, Zhou W, Brumpton BM, Rasheed H, Havulinna AS,
Veturi Y, Pacheco JA, Rosenthal EA, Lingren T, Feng Q, Kullo IJ, Narita A,
Takayama J, Martin HC, Hunt KA, Trivedi B, Haessler J, Giulianini F, Bradford Y,
Miller JE, Campbell A, Lin K, Millwood IY, Rasheed A, Hindy G, Faul JD, Zhao W,
Weir DR, Turman C, Huang H, Graff M, Choudhury A, Sengupta D, Mahajan A, Brown
MR, Zhang W, Yu K, Schmidt EM, Pandit A, Gustafsson S, Yin X, Luan J, Zhao JH,
Matsuda F, Jang HM, Yoon K, Medina-Gomez C, Pitsillides A, Hottenga JJ, Wood AR,
Ji Y, Gao Z, Haworth S, Mitchell RE, Chai JF, Aadahl M, Bjerregaard AA, Yao J,
Manichaikul A, Lee WJ, Hsiung CA, Warren HR, Ramirez J, Bork-Jensen J, Kårhus
LL, Goel A, Sabater-Lleal M, Noordam R, Mauro P, Matteo F, McDaid AF, Marques-
Vidal P, Wielscher M, Trompet S, Sattar N, Møllehave LT, Munz M, Zeng L, Huang
J, Yang B, Poveda A, Kurbasic A, Schönherr S, Forer L, Scholz M, Galesloot TE,
Bradfield JP, Ruotsalainen SE, Daw EW, Zmuda JM, Mitchell JS, Fuchsberger C,
Christensen H, Brody JA, Le P, Feitosa MF, Wojczynski MK, Hemerich D, Preuss M,
Mangino M, Christofidou P, Verweij N, Benjamins JW, Engmann J, Noah TL, Verma A,
Slieker RC, Lo KS, Zilhao NR, Kleber ME, Delgado GE, Huo S, Ikeda DD, Iha H,
Yang J, Liu J, Demirkan A, Leonard HL, Marten J, Emmel C, Schmidt B, Smyth LJ,
Cañadas-Garre M, Wang C, Nakatochi M, Wong A, Hutri-Kähönen N, Sim X, Xia R,
Huerta-Chagoya A, Fernandez-Lopez JC, Lyssenko V, Nongmaithem SS, Sankareswaran
A, Irvin MR, Oldmeadow C, Kim HN, Ryu S, Timmers PRHJ, Arbeeva L, Dorajoo R,
Lange LA, Prasad G, Lorés-Motta L, Pauper M, Long J, Li X, Theusch E, Takeuchi
F, Spracklen CN, Loukola A, Bollepalli S, Warner SC, Wang YX, Wei WB, Nutile T,
Ruggiero D, Sung YJ, Chen S, Liu F, Yang J, Kentistou KA, Banas B, Morgan A,
Meidtner K, Bielak LF, Smith JA, Hebbar P, Farmaki AE, Hofer E, Lin M, Concas
MP, Vaccargiu S, van der Most PJ, Pitkänen N, Cade BE, van der Laan SW, Chitrala
KN, Weiss S, Bentley AR, Doumatey AP, Adeyemo AA, Lee JY, Petersen ERB, Nielsen
AA, Choi HS, Nethander M, Freitag-Wolf S, Southam L, Rayner NW, Wang CA, Lin SY,
Wang JS, Couture C, Lyytikäinen LP, Nikus K, Cuellar-Partida G, Vestergaard H,
Hidalgo B, Giannakopoulou O, Cai Q, Obura MO, van Setten J, He KY, Tang H,
Terzikhan N, Shin JH, Jackson RD, Reiner AP, Martin LW, Chen Z, Li L, Kawaguchi
T, Thiery J, Bis JC, Launer LJ, Li H, Nalls MA, Raitakari OT, Ichihara S, Wild
SH, Nelson CP, Campbell H, Jäger S, Nabika T, Al-Mulla F, Niinikoski H, Braund
PS, Kolcic I, Kovacs P, Giardoglou T, Katsuya T, de Kleijn D, de Borst GJ, Kim
EK, Adams HHH, Ikram MA, Zhu X, Asselbergs FW, Kraaijeveld AO, Beulens JWJ, Shu
XO, Rallidis LS, Pedersen O, Hansen T, Mitchell P, Hewitt AW, Kähönen M, Pérusse
L, Bouchard C, Tönjes A, Ida Chen YD, Pennell CE, Mori TA, Lieb W, Franke A,
Ohlsson C, Mellström D, Cho YS, Lee H, Yuan JM, Koh WP, Rhee SY, Woo JT, Heid
IM, Stark KJ, Zimmermann ME, Völzke H, Homuth G, Evans MK, Zonderman AB, Polasek
O, Pasterkamp G, Hoefer IE, Redline S, Pahkala K, Oldehinkel AJ, Snieder H,
Biino G, Schmidt R, Schmidt H, Bandinelli S, Dedoussis G, Thanaraj TA, Peyser
PA, Kato N, Schulze MB, Girotto G, Böger CA, Jung B, Joshi PK, Bennett DA, De
Jager PL, Lu X, Mamakou V, Brown M, Caulfield MJ, Munroe PB, Guo X, Ciullo M,
Jonas JB, Samani NJ, Kaprio J, Pajukanta P, Tusié-Luna T, Aguilar-Salinas CA,
Adair LS, Bechayda SA, de Silva HJ, Wickremasinghe AR, Krauss RM, Wu JY, Zheng
W, den Hollander AI, Bharadwaj D, Correa A, Wilson JG, Lind L, Heng CK, Nelson
AE, Golightly YM, Wilson JF, Penninx B, Kim HL, Attia J, Scott RJ, Rao DC,
Arnett DK, Walker M, Scott LJ, Koistinen HA, Chandak GR, Mercader JM,
Villalpando CG, Orozco L, Fornage M, Tai ES, van Dam RM, Lehtimäki T, Chaturvedi
N, Yokota M, Liu J, Reilly DF, McKnight AJ, Kee F, Jöckel KH, McCarthy MI,
Palmer CNA, Vitart V, Hayward C, Simonsick E, van Duijn CM, Jin ZB, Lu F,
Hishigaki H, Lin X, März W, Gudnason V, Tardif JC, Lettre G, T Hart LM, Elders
PJM, Rader DJ, Damrauer SM, Kumari M, Kivimaki M, van der Harst P, Spector TD,
Loos RJF, Province MA, Parra EJ, Cruz M, Psaty BM, Brandslund I, Pramstaller PP,
Rotimi CN, Christensen K, Ripatti S, Widén E, Hakonarson H, Grant SFA, Kiemeney
L, de Graaf J, Loeffler M, Kronenberg F, Gu D, Erdmann J, Schunkert H, Franks
PW, Linneberg A, Jukema JW, Khera AV, Männikkö M, Jarvelin MR, Kutalik Z,
Francesco C, Mook-Kanamori DO, Willems van Dijk K, Watkins H, Strachan DP,
Grarup N, Sever P, Poulter N, Huey-Herng Sheu W, Rotter JI, Dantoft TM, Karpe F,
Neville MJ, Timpson NJ, Cheng CY, Wong TY, Khor CC, Li H, Sabanayagam C, Peters
A, Gieger C, Hattersley AT, Pedersen NL, Magnusson PKE, Boomsma DI, de Geus EJC,
Cupples LA, van Meurs JBJ, Ikram A, Ghanbari M, Gordon-Larsen P, Huang W, Kim
YJ, Tabara Y, Wareham NJ, Langenberg C, Zeggini E, Tuomilehto J, Kuusisto J,
Laakso M, Ingelsson E, Abecasis G, Chambers JC, Kooner JS, de Vries PS, Morrison
AC, Hazelhurst S, Ramsay M, North KE, Daviglus M, Kraft P, Martin NG, Whitfield
JB, Abbas S, Saleheen D, Walters RG, Holmes MV, Black C, Smith BH, Baras A,
Justice AE, Buring JE, Ridker PM, Chasman DI, Kooperberg C, Tamiya G, Yamamoto
M, van Heel DA, Trembath RC, Wei WQ, Jarvik GP, Namjou B, Hayes MG, Ritchie MD,
Jousilahti P, Salomaa V, Hveem K, Åsvold BO, Kubo M, Kamatani Y, Okada Y,
Murakami Y, Kim BJ, Thorsteinsdottir U, Stefansson K, Zhang J, Chen YE, Ho YL,
Lynch JA, Tsao PS, Chang KM, Cho K, O'Donnell CJ, Gaziano JM, Wilson P, Mohlke
KL, Frayling TM, Hirschhorn JN, Kathiresan S, Boehnke M; Million Veterans
Program; Global Lipids Genetics Consortium, Struan Grant, Natarajan P, Sun YV,
Morris AP, Deloukas P, Peloso G, Assimes TL, Willer CJ, Zhu X, Brown CD. A
multi-layer functional genomic analysis to understand noncoding genetic
variation in lipids. Am J Hum Genet. 2022 Aug 4;109(8):1366-1387. doi:
10.1016/j.ajhg.2022.06.012. PMID: 35931049; PMCID: PMC9388392.

5: Ritsch A, Hunjadi M, Stojakovic T, Scherberich JE, Silbernagel G, Scharnagl
H, Delgado GE, Kleber ME, März W. Independent Effects of Kidney Function and
Cholesterol Efflux on Cardiovascular Mortality. Biomedicines. 2022 Jul
29;10(8):1832. doi: 10.3390/biomedicines10081832. PMID: 36009383; PMCID:
PMC9404976.

6: Yazdani B, Kleber ME, Yücel G, Delgado GE, Husain-Syed F, Krüger B, März W,
Schwenke K, Sigl M, Krämer BK. Polyvascular disease, pulse pressure and
mortality. Vasa. 2022 Jul;51(4):229-238. doi: 10.1024/0301-1526/a001011. Epub
2022 May 23. PMID: 35603601.

7: Dam V, Onland-Moret NC, Burgess S, Chirlaque MD, Peters SAE, Schuit E, Tikk
K, Weiderpass E, Oliver-Williams C, Wood AM, Tjønneland A, Dahm CC, Overvad K,
Boutron-Ruault MC, Schulze MB, Trichopoulou A, Ferrari P, Masala G, Krogh V,
Tumino R, Matullo G, Panico S, Boer JMA, Verschuren WMM, Waaseth M, Pérez MJS,
Amiano P, Imaz L, Moreno-Iribas C, Melander O, Harlid S, Nordendahl M, Wennberg
P, Key TJ, Riboli E, Santiuste C, Kaaks R, Katzke V, Langenberg C, Wareham NJ,
Schunkert H, Erdmann J, Willenborg C, Hengstenberg C, Kleber ME, Delgado G, März
W, Kanoni S, Dedoussis G, Deloukas P, Nikpay M, McPherson R, Scholz M, Teren A,
Butterworth AS, van der Schouw YT. Genetically Determined Reproductive Aging and
Coronary Heart Disease: A Bidirectional 2-sample Mendelian Randomization. J Clin
Endocrinol Metab. 2022 Jun 16;107(7):e2952-e2961. doi: 10.1210/clinem/dgac171.
PMID: 35306566; PMCID: PMC9202700.

8: Winkler TW, Rasheed H, Teumer A, Gorski M, Rowan BX, Stanzick KJ, Thomas LF,
Tin A, Hoppmann A, Chu AY, Tayo B, Thio CHL, Cusi D, Chai JF, Sieber KB, Horn K,
Li M, Scholz M, Cocca M, Wuttke M, van der Most PJ, Yang Q, Ghasemi S, Nutile T,
Li Y, Pontali G, Günther F, Dehghan A, Correa A, Parsa A, Feresin A, de Vries
APJ, Zonderman AB, Smith AV, Oldehinkel AJ, De Grandi A, Rosenkranz AR, Franke
A, Teren A, Metspalu A, Hicks AA, Morris AP, Tönjes A, Morgan A, Podgornaia AI,
Peters A, Körner A, Mahajan A, Campbell A, Freedman BI, Spedicati B, Ponte B,
Schöttker B, Brumpton B, Banas B, Krämer BK, Jung B, Åsvold BO, Smith BH, Ning
B, Penninx BWJH, Vanderwerff BR, Psaty BM, Kammerer CM, Langefeld CD, Hayward C,
Spracklen CN, Robinson-Cohen C, Hartman CA, Lindgren CM, Wang C, Sabanayagam C,
Heng CK, Lanzani C, Khor CC, Cheng CY, Fuchsberger C, Gieger C, Shaffer CM,
Schulz CA, Willer CJ, Chasman DI, Gudbjartsson DF, Ruggiero D, Toniolo D,
Czamara D, Porteous DJ, Waterworth DM, Mascalzoni D, Mook-Kanamori DO, Reilly
DF, Daw EW, Hofer E, Boerwinkle E, Salvi E, Bottinger EP, Tai ES, Catamo E,
Rizzi F, Guo F, Rivadeneira F, Guilianini F, Sveinbjornsson G, Ehret G, Waeber
G, Biino G, Girotto G, Pistis G, Nadkarni GN, Delgado GE, Montgomery GW, Snieder
H, Campbell H, White HD, Gao H, Stringham HM, Schmidt H, Li H, Brenner H, Holm
H, Kirsten H, Kramer H, Rudan I, Nolte IM, Tzoulaki I, Olafsson I, Martins J,
Cook JP, Wilson JF, Halbritter J, Felix JF, Divers J, Kooner JS, Lee JJ,
O'Connell J, Rotter JI, Liu J, Xu J, Thiery J, Ärnlöv J, Kuusisto J,
Jakobsdottir J, Tremblay J, Chambers JC, Whitfield JB, Gaziano JM, Marten J,
Coresh J, Jonas JB, Mychaleckyj JC, Christensen K, Eckardt KU, Mohlke KL,
Endlich K, Dittrich K, Ryan KA, Rice KM, Taylor KD, Ho K, Nikus K, Matsuda K,
Strauch K, Miliku K, Hveem K, Lind L, Wallentin L, Yerges-Armstrong LM, Raffield
LM, Phillips LS, Launer LJ, Lyytikäinen LP, Lange LA, Citterio L, Klaric L,
Ikram MA, Ising M, Kleber ME, Francescatto M, Concas MP, Ciullo M, Piratsu M,
Orho-Melander M, Laakso M, Loeffler M, Perola M, de Borst MH, Gögele M, Bianca
M, Lukas MA, Feitosa MF, Biggs ML, Wojczynski MK, Kavousi M, Kanai M, Akiyama M,
Yasuda M, Nauck M, Waldenberger M, Chee ML, Chee ML, Boehnke M, Preuss MH,
Stumvoll M, Province MA, Evans MK, O'Donoghue ML, Kubo M, Kähönen M, Kastarinen
M, Nalls MA, Kuokkanen M, Ghanbari M, Bochud M, Josyula NS, Martin NG, Tan NYQ,
Palmer ND, Pirastu N, Schupf N, Verweij N, Hutri-Kähönen N, Mononen N, Bansal N,
Devuyst O, Melander O, Raitakari OT, Polasek O, Manunta P, Gasparini P, Mishra
PP, Sulem P, Magnusson PKE, Elliott P, Ridker PM, Hamet P, Svensson PO, Joshi
PK, Kovacs P, Pramstaller PP, Rossing P, Vollenweider P, van der Harst P,
Dorajoo R, Sim RZH, Burkhardt R, Tao R, Noordam R, Mägi R, Schmidt R, de Mutsert
R, Rueedi R, van Dam RM, Carroll RJ, Gansevoort RT, Loos RJF, Felicita SC,
Sedaghat S, Padmanabhan S, Freitag-Wolf S, Pendergrass SA, Graham SE, Gordon SD,
Hwang SJ, Kerr SM, Vaccargiu S, Patil SB, Hallan S, Bakker SJL, Lim SC, Lucae S,
Vogelezang S, Bergmann S, Corre T, Ahluwalia TS, Lehtimäki T, Boutin TS,
Meitinger T, Wong TY, Bergler T, Rabelink TJ, Esko T, Haller T, Thorsteinsdottir
U, Völker U, Foo VHX, Salomaa V, Vitart V, Giedraitis V, Gudnason V, Jaddoe VWV,
Huang W, Zhang W, Wei WB, Kiess W, März W, Koenig W, Lieb W, Gao X, Sim X, Wang
YX, Friedlander Y, Tham YC, Kamatani Y, Okada Y, Milaneschi Y, Yu Z; Lifelines
cohort study; DiscovEHR/MyCode study; VA Million Veteran Program, Stark KJ,
Stefansson K, Böger CA, Hung AM, Kronenberg F, Köttgen A, Pattaro C, Heid IM.
Differential and shared genetic effects on kidney function between diabetic and
non-diabetic individuals. Commun Biol. 2022 Jun 13;5(1):580. doi:
10.1038/s42003-022-03448-z. PMID: 35697829; PMCID: PMC9192715.

9: Silbernagel G, Scharnagl H, Saely CH, Reinthaler M, Rief M, Kleber ME,
Larcher B, Chapman J, Schaefer JR, Drexel H, März W. The LDL Apolipoprotein
B-to-LDL Cholesterol Ratio: Association with Cardiovascular Mortality and a
Biomarker of Small, Dense LDLs. Biomedicines. 2022 Jun 2;10(6):1302. doi:
10.3390/biomedicines10061302. PMID: 35740324; PMCID: PMC9220033.

10: Li Y, Cheng Y, Consolato F, Schiano G, Chong MR, Pietzner M, Nguyen NQH,
Scherer N, Biggs ML, Kleber ME, Haug S, Göçmen B, Pigeyre M, Sekula P,
Steinbrenner I, Schlosser P, Joseph CB, Brody JA, Grams ME, Hayward C,
Schultheiss UT, Krämer BK, Kronenberg F, Peters A, Seissler J, Steubl D, Then C,
Wuttke M, März W, Eckardt KU, Gieger C, Boerwinkle E, Psaty BM, Coresh J, Oefner
PJ, Pare G, Langenberg C, Scherberich JE, Yu B, Akilesh S, Devuyst O, Rampoldi
L, Köttgen A. Genome-wide studies reveal factors associated with circulating
uromodulin and its relationships to complex diseases. JCI Insight. 2022 May
23;7(10):e157035. doi: 10.1172/jci.insight.157035. PMID: 35446786; PMCID:
PMC9220927.

11: Laaksonen J, Mishra PP, Seppälä I, Raitoharju E, Marttila S, Mononen N,
Lyytikäinen LP, Kleber ME, Delgado GE, Lepistö M, Almusa H, Ellonen P, Lorkowski
S, März W, Hutri-Kähönen N, Raitakari O, Kähönen M, Salonen JT, Lehtimäki T.
Mitochondrial genome-wide analysis of nuclear DNA methylation quantitative trait
loci. Hum Mol Genet. 2022 May 19;31(10):1720-1732. doi: 10.1093/hmg/ddab339.
PMID: 35077545; PMCID: PMC9122653.

12: Moissl AP, Delgado GE, Krämer BK, Dawczynski C, Stojakovic T, März W, Kleber
ME, Lorkowski S. Gender- and subgroup-specific sensitivity analysis of alcohol
consumption and mortality in the Ludwigshafen Risk and Cardiovascular Health
(LURIC) study. Data Brief. 2022 Jan 26;41:107873. doi:
10.1016/j.dib.2022.107873. PMID: 35198663; PMCID: PMC8841993.

13: Hilvo M, Lääperi M, Jylhä A, Kleber ME, Hurme R, Scharnagl H, März W,
Sinisalo J, Laaksonen R. Prior myocardial infarction, coronary artery disease
extent, diabetes mellitus, and CERT2 score for risk stratification in stable
coronary artery disease. Eur J Prev Cardiol. 2022 Mar 30;29(4):e159-e162. doi:
10.1093/eurjpc/zwab122. PMID: 34453528.

14: Pott J, Gådin JR, Theusch E, Kleber ME, Delgado GE, Kirsten H, Hauck SM,
Burkhardt R, Scharnagl H, Krauss RM, Loeffler M, März W, Thiery J, Silveira A,
Van't Hooft FM, Scholz M. Meta-GWAS of PCSK9 levels detects two novel loci at
APOB and TM6SF2. Hum Mol Genet. 2022 Mar 21;31(6):999-1011. doi:
10.1093/hmg/ddab279. PMID: 34590679; PMCID: PMC8947322.

15: Zeng L, Moser S, Mirza-Schreiber N, Lamina C, Coassin S, Nelson CP, Annilo
T, Franzén O, Kleber ME, Mack S, Andlauer TFM, Jiang B, Stiller B, Li L,
Willenborg C, Munz M, Kessler T, Kastrati A, Laugwitz KL, Erdmann J, Moebus S,
Nöthen MM, Peters A, Strauch K, Müller-Nurasyid M, Gieger C, Meitinger T,
Steinhagen-Thiessen E, März W, Metspalu A, Björkegren JLM, Samani NJ, Kronenberg
F, Müller-Myhsok B, Schunkert H. Cis-epistasis at the LPA locus and risk of
cardiovascular diseases. Cardiovasc Res. 2022 Mar 16;118(4):1088-1102. doi:
10.1093/cvr/cvab136. PMID: 33878186; PMCID: PMC8930071.

16: Silbernagel G, Scharnagl H, Kleber ME, Hoffmann MM, Delgado GE, Stojakovic
T, Gary T, Zeng L, Ritsch A, Zewinger S, Speer T, Schunkert H, Landmesser U,
März W, Grammer TB. J-shaped association between circulating apoC-III and
cardiovascular mortality. Eur J Prev Cardiol. 2022 Mar 11;29(2):e68-e71. doi:
10.1093/eurjpc/zwaa169. PMID: 33609030.

17: Krohn JB, Nguyen YN, Akhavanpoor M, Erbel C, Domschke G, Linden F, Kleber
ME, Delgado G, März W, Katus HA, Gleissner CA. Identification of Specific
Coronary Artery Disease Phenotypes Implicating Differential Pathophysiologies.
Front Cardiovasc Med. 2022 Mar 10;9:778206. doi: 10.3389/fcvm.2022.778206. PMID:
35355960; PMCID: PMC8960070.

18: Scholz M, Horn K, Pott J, Gross A, Kleber ME, Delgado GE, Mishra PP, Kirsten
H, Gieger C, Müller-Nurasyid M, Tönjes A, Kovacs P, Lehtimäki T, Raitakari O,
Kähönen M, Gylling H, Baber R, Isermann B, Stumvoll M, Loeffler M, März W,
Meitinger T, Peters A, Thiery J, Teupser D, Ceglarek U. Author Correction:
Genome-wide meta-analysis of phytosterols reveals five novel loci and a
detrimental effect on coronary atherosclerosis. Nat Commun. 2022 Feb
25;13(1):1122. doi: 10.1038/s41467-022-28863-y. Erratum for: Nat Commun. 2022
Jan 10;13(1):143. PMID: 35217655; PMCID: PMC8881461.

19: Scholz M, Horn K, Pott J, Gross A, Kleber ME, Delgado GE, Mishra PP, Kirsten
H, Gieger C, Müller-Nurasyid M, Tönjes A, Kovacs P, Lehtimäki T, Raitakari O,
Kähönen M, Gylling H, Baber R, Isermann B, Stumvoll M, Loeffler M, März W,
Meitinger T, Peters A, Thiery J, Teupser D, Ceglarek U. Genome-wide meta-
analysis of phytosterols reveals five novel loci and a detrimental effect on
coronary atherosclerosis. Nat Commun. 2022 Jan 10;13(1):143. doi:
10.1038/s41467-021-27706-6. Erratum in: Nat Commun. 2022 Feb 25;13(1):1122.
PMID: 35013273; PMCID: PMC8748632.
2021
1: Schlosser P, Tin A, Matias-Garcia PR, Thio CHL, Joehanes R, Liu H, Weihs A,
Yu Z, Hoppmann A, Grundner-Culemann F, Min JL, Adeyemo AA, Agyemang C, Ärnlöv J,
Aziz NA, Baccarelli A, Bochud M, Brenner H, Breteler MMB, Carmeli C, Chaker L,
Chambers JC, Cole SA, Coresh J, Corre T, Correa A, Cox SR, de Klein N, Delgado
GE, Domingo-Relloso A, Eckardt KU, Ekici AB, Endlich K, Evans KL, Floyd JS,
Fornage M, Franke L, Fraszczyk E, Gao X, Gào X, Ghanbari M, Ghasemi S, Gieger C,
Greenland P, Grove ML, Harris SE, Hemani G, Henneman P, Herder C, Horvath S, Hou
L, Hurme MA, Hwang SJ, Jarvelin MR, Kardia SLR, Kasela S, Kleber ME, Koenig W,
Kooner JS, Kramer H, Kronenberg F, Kühnel B, Lehtimäki T, Lind L, Liu D, Liu Y,
Lloyd-Jones DM, Lohman K, Lorkowski S, Lu AT, Marioni RE, März W, McCartney DL,
Meeks KAC, Milani L, Mishra PP, Nauck M, Navas-Acien A, Nowak C, Peters A,
Prokisch H, Psaty BM, Raitakari OT, Ratliff SM, Reiner AP, Rosas SE, Schöttker
B, Schwartz J, Sedaghat S, Smith JA, Sotoodehnia N, Stocker HR, Stringhini S,
Sundström J, Swenson BR, Tellez-Plaza M, van Meurs JBJ, van Vliet-Ostaptchouk
JV, Venema A, Verweij N, Walker RM, Wielscher M, Winkelmann J, Wolffenbuttel
BHR, Zhao W, Zheng Y; Estonian Biobank Research Team; Genetics of DNA
Methylation Consortium, Loh M, Snieder H, Levy D, Waldenberger M, Susztak K,
Köttgen A, Teumer A. Meta-analyses identify DNA methylation associated with
kidney function and damage. Nat Commun. 2021 Dec 9;12(1):7174. doi:
10.1038/s41467-021-27234-3. PMID: 34887417; PMCID: PMC8660832.

2: Tin A, Schlosser P, Matias-Garcia PR, Thio CHL, Joehanes R, Liu H, Yu Z,
Weihs A, Hoppmann A, Grundner-Culemann F, Min JL, Kuhns VLH, Adeyemo AA,
Agyemang C, Ärnlöv J, Aziz NA, Baccarelli A, Bochud M, Brenner H, Bressler J,
Breteler MMB, Carmeli C, Chaker L, Coresh J, Corre T, Correa A, Cox SR, Delgado
GE, Eckardt KU, Ekici AB, Endlich K, Floyd JS, Fraszczyk E, Gao X, Gào X, Gelber
AC, Ghanbari M, Ghasemi S, Gieger C, Greenland P, Grove ML, Harris SE, Hemani G,
Henneman P, Herder C, Horvath S, Hou L, Hurme MA, Hwang SJ, Kardia SLR, Kasela
S, Kleber ME, Koenig W, Kooner JS, Kronenberg F, Kühnel B, Ladd-Acosta C,
Lehtimäki T, Lind L, Liu D, Lloyd-Jones DM, Lorkowski S, Lu AT, Marioni RE, März
W, McCartney DL, Meeks KAC, Milani L, Mishra PP, Nauck M, Nowak C, Peters A,
Prokisch H, Psaty BM, Raitakari OT, Ratliff SM, Reiner AP, Schöttker B, Schwartz
J, Sedaghat S, Smith JA, Sotoodehnia N, Stocker HR, Stringhini S, Sundström J,
Swenson BR, van Meurs JBJ, van Vliet-Ostaptchouk JV, Venema A, Völker U,
Winkelmann J, Wolffenbuttel BHR, Zhao W, Zheng Y; Estonian Biobank Research
Team; Genetics of DNA Methylation Consortium, Loh M, Snieder H, Waldenberger M,
Levy D, Akilesh S, Woodward OM, Susztak K, Teumer A, Köttgen A. Epigenome-wide
association study of serum urate reveals insights into urate co-regulation and
the SLC2A9 locus. Nat Commun. 2021 Dec 9;12(1):7173. doi:
10.1038/s41467-021-27198-4. PMID: 34887389; PMCID: PMC8660809.

3: Graham SE, Clarke SL, Wu KH, Kanoni S, Zajac GJM, Ramdas S, Surakka I, Ntalla
I, Vedantam S, Winkler TW, Locke AE, Marouli E, Hwang MY, Han S, Narita A,
Choudhury A, Bentley AR, Ekoru K, Verma A, Trivedi B, Martin HC, Hunt KA, Hui Q,
Klarin D, Zhu X, Thorleifsson G, Helgadottir A, Gudbjartsson DF, Holm H,
Olafsson I, Akiyama M, Sakaue S, Terao C, Kanai M, Zhou W, Brumpton BM, Rasheed
H, Ruotsalainen SE, Havulinna AS, Veturi Y, Feng Q, Rosenthal EA, Lingren T,
Pacheco JA, Pendergrass SA, Haessler J, Giulianini F, Bradford Y, Miller JE,
Campbell A, Lin K, Millwood IY, Hindy G, Rasheed A, Faul JD, Zhao W, Weir DR,
Turman C, Huang H, Graff M, Mahajan A, Brown MR, Zhang W, Yu K, Schmidt EM,
Pandit A, Gustafsson S, Yin X, Luan J, Zhao JH, Matsuda F, Jang HM, Yoon K,
Medina-Gomez C, Pitsillides A, Hottenga JJ, Willemsen G, Wood AR, Ji Y, Gao Z,
Haworth S, Mitchell RE, Chai JF, Aadahl M, Yao J, Manichaikul A, Warren HR,
Ramirez J, Bork-Jensen J, Kårhus LL, Goel A, Sabater-Lleal M, Noordam R, Sidore
C, Fiorillo E, McDaid AF, Marques-Vidal P, Wielscher M, Trompet S, Sattar N,
Møllehave LT, Thuesen BH, Munz M, Zeng L, Huang J, Yang B, Poveda A, Kurbasic A,
Lamina C, Forer L, Scholz M, Galesloot TE, Bradfield JP, Daw EW, Zmuda JM,
Mitchell JS, Fuchsberger C, Christensen H, Brody JA, Feitosa MF, Wojczynski MK,
Preuss M, Mangino M, Christofidou P, Verweij N, Benjamins JW, Engmann J, Kember
RL, Slieker RC, Lo KS, Zilhao NR, Le P, Kleber ME, Delgado GE, Huo S, Ikeda DD,
Iha H, Yang J, Liu J, Leonard HL, Marten J, Schmidt B, Arendt M, Smyth LJ,
Cañadas-Garre M, Wang C, Nakatochi M, Wong A, Hutri-Kähönen N, Sim X, Xia R,
Huerta-Chagoya A, Fernandez-Lopez JC, Lyssenko V, Ahmed M, Jackson AU, Irvin MR,
Oldmeadow C, Kim HN, Ryu S, Timmers PRHJ, Arbeeva L, Dorajoo R, Lange LA, Chai
X, Prasad G, Lorés-Motta L, Pauper M, Long J, Li X, Theusch E, Takeuchi F,
Spracklen CN, Loukola A, Bollepalli S, Warner SC, Wang YX, Wei WB, Nutile T,
Ruggiero D, Sung YJ, Hung YJ, Chen S, Liu F, Yang J, Kentistou KA, Gorski M,
Brumat M, Meidtner K, Bielak LF, Smith JA, Hebbar P, Farmaki AE, Hofer E, Lin M,
Xue C, Zhang J, Concas MP, Vaccargiu S, van der Most PJ, Pitkänen N, Cade BE,
Lee J, van der Laan SW, Chitrala KN, Weiss S, Zimmermann ME, Lee JY, Choi HS,
Nethander M, Freitag-Wolf S, Southam L, Rayner NW, Wang CA, Lin SY, Wang JS,
Couture C, Lyytikäinen LP, Nikus K, Cuellar-Partida G, Vestergaard H, Hildalgo
B, Giannakopoulou O, Cai Q, Obura MO, van Setten J, Li X, Schwander K, Terzikhan
N, Shin JH, Jackson RD, Reiner AP, Martin LW, Chen Z, Li L, Highland HM, Young
KL, Kawaguchi T, Thiery J, Bis JC, Nadkarni GN, Launer LJ, Li H, Nalls MA,
Raitakari OT, Ichihara S, Wild SH, Nelson CP, Campbell H, Jäger S, Nabika T, Al-
Mulla F, Niinikoski H, Braund PS, Kolcic I, Kovacs P, Giardoglou T, Katsuya T,
Bhatti KF, de Kleijn D, de Borst GJ, Kim EK, Adams HHH, Ikram MA, Zhu X,
Asselbergs FW, Kraaijeveld AO, Beulens JWJ, Shu XO, Rallidis LS, Pedersen O,
Hansen T, Mitchell P, Hewitt AW, Kähönen M, Pérusse L, Bouchard C, Tönjes A,
Chen YI, Pennell CE, Mori TA, Lieb W, Franke A, Ohlsson C, Mellström D, Cho YS,
Lee H, Yuan JM, Koh WP, Rhee SY, Woo JT, Heid IM, Stark KJ, Völzke H, Homuth G,
Evans MK, Zonderman AB, Polasek O, Pasterkamp G, Hoefer IE, Redline S, Pahkala
K, Oldehinkel AJ, Snieder H, Biino G, Schmidt R, Schmidt H, Chen YE, Bandinelli
S, Dedoussis G, Thanaraj TA, Kardia SLR, Kato N, Schulze MB, Girotto G, Jung B,
Böger CA, Joshi PK, Bennett DA, De Jager PL, Lu X, Mamakou V, Brown M, Caulfield
MJ, Munroe PB, Guo X, Ciullo M, Jonas JB, Samani NJ, Kaprio J, Pajukanta P,
Adair LS, Bechayda SA, de Silva HJ, Wickremasinghe AR, Krauss RM, Wu JY, Zheng
W, den Hollander AI, Bharadwaj D, Correa A, Wilson JG, Lind L, Heng CK, Nelson
AE, Golightly YM, Wilson JF, Penninx B, Kim HL, Attia J, Scott RJ, Rao DC,
Arnett DK, Walker M, Koistinen HA, Chandak GR, Yajnik CS, Mercader JM, Tusié-
Luna T, Aguilar-Salinas CA, Villalpando CG, Orozco L, Fornage M, Tai ES, van Dam
RM, Lehtimäki T, Chaturvedi N, Yokota M, Liu J, Reilly DF, McKnight AJ, Kee F,
Jöckel KH, McCarthy MI, Palmer CNA, Vitart V, Hayward C, Simonsick E, van Duijn
CM, Lu F, Qu J, Hishigaki H, Lin X, März W, Parra EJ, Cruz M, Gudnason V, Tardif
JC, Lettre G, 't Hart LM, Elders PJM, Damrauer SM, Kumari M, Kivimaki M, van der
Harst P, Spector TD, Loos RJF, Province MA, Psaty BM, Brandslund I, Pramstaller
PP, Christensen K, Ripatti S, Widén E, Hakonarson H, Grant SFA, Kiemeney LALM,
de Graaf J, Loeffler M, Kronenberg F, Gu D, Erdmann J, Schunkert H, Franks PW,
Linneberg A, Jukema JW, Khera AV, Männikkö M, Jarvelin MR, Kutalik Z, Cucca F,
Mook-Kanamori DO, van Dijk KW, Watkins H, Strachan DP, Grarup N, Sever P,
Poulter N, Rotter JI, Dantoft TM, Karpe F, Neville MJ, Timpson NJ, Cheng CY,
Wong TY, Khor CC, Sabanayagam C, Peters A, Gieger C, Hattersley AT, Pedersen NL,
Magnusson PKE, Boomsma DI, de Geus EJC, Cupples LA, van Meurs JBJ, Ghanbari M,
Gordon-Larsen P, Huang W, Kim YJ, Tabara Y, Wareham NJ, Langenberg C, Zeggini E,
Kuusisto J, Laakso M, Ingelsson E, Abecasis G, Chambers JC, Kooner JS, de Vries
PS, Morrison AC, North KE, Daviglus M, Kraft P, Martin NG, Whitfield JB, Abbas
S, Saleheen D, Walters RG, Holmes MV, Black C, Smith BH, Justice AE, Baras A,
Buring JE, Ridker PM, Chasman DI, Kooperberg C, Wei WQ, Jarvik GP, Namjou B,
Hayes MG, Ritchie MD, Jousilahti P, Salomaa V, Hveem K, Åsvold BO, Kubo M,
Kamatani Y, Okada Y, Murakami Y, Thorsteinsdottir U, Stefansson K, Ho YL, Lynch
JA, Rader DJ, Tsao PS, Chang KM, Cho K, O'Donnell CJ, Gaziano JM, Wilson P,
Rotimi CN, Hazelhurst S, Ramsay M, Trembath RC, van Heel DA, Tamiya G, Yamamoto
M, Kim BJ, Mohlke KL, Frayling TM, Hirschhorn JN, Kathiresan S; VA Million
Veteran Program; Global Lipids Genetics Consortium*, Boehnke M, Natarajan P,
Peloso GM, Brown CD, Morris AP, Assimes TL, Deloukas P, Sun YV, Willer CJ. The
power of genetic diversity in genome-wide association studies of lipids. Nature.
2021 Dec;600(7890):675-679. doi: 10.1038/s41586-021-04064-3. Epub 2021 Dec 9.
PMID: 34887591; PMCID: PMC8730582.

4: Lumbers RT, Shah S, Lin H, Czuba T, Henry A, Swerdlow DI, Mälarstig A,
Andersson C, Verweij N, Holmes MV, Ärnlöv J, Svensson P, Hemingway H, Sallah N,
Almgren P, Aragam KG, Asselin G, Backman JD, Biggs ML, Bloom HL, Boersma E,
Brandimarto J, Brown MR, Brunner-La Rocca HP, Carey DJ, Chaffin MD, Chasman DI,
Chazara O, Chen X, Chen X, Chung JH, Chutkow W, Cleland JGF, Cook JP, de Denus
S, Dehghan A, Delgado GE, Denaxas S, Doney AS, Dörr M, Dudley SC, Engström G,
Esko T, Fatemifar G, Felix SB, Finan C, Ford I, Fougerousse F, Fouodjio R,
Ghanbari M, Ghasemi S, Giedraitis V, Giulianini F, Gottdiener JS, Gross S,
Guðbjartsson DF, Gui H, Gutmann R, Haggerty CM, van der Harst P, Hedman ÅK,
Helgadottir A, Hillege H, Hyde CL, Jacob J, Jukema JW, Kamanu F, Kardys I,
Kavousi M, Khaw KT, Kleber ME, Køber L, Koekemoer A, Kraus B, Kuchenbaecker K,
Langenberg C, Lind L, Lindgren CM, London B, Lotta LA, Lovering RC, Luan J,
Magnusson P, Mahajan A, Mann D, Margulies KB, Marston NA, März W, McMurray JJV,
Melander O, Melloni G, Mordi IR, Morley MP, Morris AD, Morris AP, Morrison AC,
Nagle MW, Nelson CP, Newton-Cheh C, Niessner A, Niiranen T, Nowak C, O'Donoghue
ML, Owens AT, Palmer CNA, Paré G, Perola M, Perreault LL, Portilla-Fernandez E,
Psaty BM, Rice KM, Ridker PM, Romaine SPR, Roselli C, Rotter JI, Ruff CT,
Sabatine MS, Salo P, Salomaa V, van Setten J, Shalaby AA, Smelser DT, Smith NL,
Stefansson K, Stender S, Stott DJ, Sveinbjörnsson G, Tammesoo ML, Tardif JC,
Taylor KD, Teder-Laving M, Teumer A, Thorgeirsson G, Thorsteinsdottir U, Torp-
Pedersen C, Trompet S, Tuckwell D, Tyl B, Uitterlinden AG, Vaura F, Veluchamy A,
Visscher PM, Völker U, Voors AA, Wang X, Wareham NJ, Weeke PE, Weiss R, White
HD, Wiggins KL, Xing H, Yang J, Yang Y, Yerges-Armstrong LM, Yu B, Zannad F,
Zhao F; Regeneron Genetics Center, Wilk JB, Holm H, Sattar N, Lubitz SA, Lanfear
DE, Shah S, Dunn ME, Wells QS, Asselbergs FW, Hingorani AD, Dubé MP, Samani NJ,
Lang CC, Cappola TP, Ellinor PT, Vasan RS, Smith JG. The genomics of heart
failure: design and rationale of the HERMES consortium. ESC Heart Fail. 2021
Dec;8(6):5531-5541. doi: 10.1002/ehf2.13517. Epub 2021 Sep 3. PMID: 34480422;
PMCID: PMC8712846.

5: Hall IF, Climent M, Viviani Anselmi C, Papa L, Tragante V, Lambroia L, Farina
FM, Kleber ME, März W, Biguori C, Condorelli G, Elia L. rs41291957 controls
miR-143 and miR-145 expression and impacts coronary artery disease risk. EMBO
Mol Med. 2021 Oct 7;13(10):e14060. doi: 10.15252/emmm.202114060. Epub 2021 Sep
22. PMID: 34551209; PMCID: PMC8495461.

6: Moissl AP, Delgado GE, Krämer BK, Dawczynski C, Stojakovic T, März W, Kleber
ME, Lorkowski S. Alcohol consumption and mortality: The Ludwigshafen Risk and
Cardiovascular Health (LURIC) study. Atherosclerosis. 2021 Oct;335:119-125. doi:
10.1016/j.atherosclerosis.2021.08.014. Epub 2021 Aug 12. PMID: 34454737.

7: Yazdani B, Delgado GE, Scharnagl H, Krämer BK, Drexel H, März W, Scherberich
JE, Leiherer A, Kleber ME. Combined Use of Serum Uromodulin and eGFR to Estimate
Mortality Risk. Front Med (Lausanne). 2021 Sep 8;8:723546. doi:
10.3389/fmed.2021.723546. PMID: 34568379; PMCID: PMC8455921.

8: Delgado GE, Kleber ME, Moissl AP, Yazdani B, Kusnik A, Ebert MP, März W,
Krämer BK, Lammert A, Teufel A. Surrogate scores of advanced fibrosis in
NAFLD/NASH do not predict mortality in patients with medium-to-high
cardiovascular risk. Am J Physiol Gastrointest Liver Physiol. 2021 Sep
1;321(4):G252-G261. doi: 10.1152/ajpgi.00058.2021. Epub 2021 Jun 16. PMID:
34132110.

9: Lanser L, Fuchs D, Scharnagl H, Grammer T, Kleber ME, März W, Weiss G, Kurz
K. Anemia of Chronic Disease in Patients With Cardiovascular Disease. Front
Cardiovasc Med. 2021 Aug 12;8:666638. doi: 10.3389/fcvm.2021.666638. PMID:
34458328; PMCID: PMC8387678.

10: Thibord F, Song C, Pattee J, Rodriguez BAT, Chen MH, O'Donnell CJ, Kleber
ME, Delgado GE, Guo X, Yao J, Taylor KD, Ozel AB, Brody JA, McKnight B, Gyorgy
B, Simonsick E, Leonard HL, Carrasquilla GD, Guindo-Martinez M, Silveira A,
Temprano-Sagrera G, Yanek LR, Becker DM, Mathias RA, Becker LC, Raffield LM,
Kilpeläinen TO, Grarup N, Pedersen O, Hansen T, Linneberg A, Hamsten A, Watkins
H, Sabater-Lleal M, Nalls MA, Trégouët DA, Morange PE, Psaty BM, Tracy RP, Smith
NL, Desch KC, Cushman M, Rotter JI, de Vries PS, Pankratz ND, Folsom AR,
Morrison AC, März W, Tang W, Johnson AD. FGL1 as a modulator of plasma D-dimer
levels: Exome-wide marker analysis of plasma tPA, PAI-1, and D-dimer. J Thromb
Haemost. 2021 Aug;19(8):2019-2028. doi: 10.1111/jth.15345. Epub 2021 May 30.
PMID: 33876560.

11: Katzmann JL, Mason AM, März W, Kleber ME, Niessner A, Blüher M, Speer T,
Laufs U. Genetic Variation in Sodium-glucose Cotransporter 2 and Heart Failure.
Clin Pharmacol Ther. 2021 Jul;110(1):149-158. doi: 10.1002/cpt.2153. Epub 2021
Feb 1. PMID: 33405238.

12: Delgado GE, Krämer BK, März W, Hellstern P, Kleber ME, Leipe J. Immune
Status and Mortality in Smokers, Ex-smokers, and Never-Smokers: The Ludwigshafen
Risk and Cardiovascular Health Study. Nicotine Tob Res. 2021 Jun
8;23(7):1191-1198. doi: 10.1093/ntr/ntab011. PMID: 33460442.

13: Chen J, Spracklen CN, Marenne G, Varshney A, Corbin LJ, Luan J, Willems SM,
Wu Y, Zhang X, Horikoshi M, Boutin TS, Mägi R, Waage J, Li-Gao R, Chan KHK, Yao
J, Anasanti MD, Chu AY, Claringbould A, Heikkinen J, Hong J, Hottenga JJ, Huo S,
Kaakinen MA, Louie T, März W, Moreno-Macias H, Ndungu A, Nelson SC, Nolte IM,
North KE, Raulerson CK, Ray D, Rohde R, Rybin D, Schurmann C, Sim X, Southam L,
Stewart ID, Wang CA, Wang Y, Wu P, Zhang W, Ahluwalia TS, Appel EVR, Bielak LF,
Brody JA, Burtt NP, Cabrera CP, Cade BE, Chai JF, Chai X, Chang LC, Chen CH,
Chen BH, Chitrala KN, Chiu YF, de Haan HG, Delgado GE, Demirkan A, Duan Q,
Engmann J, Fatumo SA, Gayán J, Giulianini F, Gong JH, Gustafsson S, Hai Y,
Hartwig FP, He J, Heianza Y, Huang T, Huerta-Chagoya A, Hwang MY, Jensen RA,
Kawaguchi T, Kentistou KA, Kim YJ, Kleber ME, Kooner IK, Lai S, Lange LA,
Langefeld CD, Lauzon M, Li M, Ligthart S, Liu J, Loh M, Long J, Lyssenko V,
Mangino M, Marzi C, Montasser ME, Nag A, Nakatochi M, Noce D, Noordam R, Pistis
G, Preuss M, Raffield L, Rasmussen-Torvik LJ, Rich SS, Robertson NR, Rueedi R,
Ryan K, Sanna S, Saxena R, Schraut KE, Sennblad B, Setoh K, Smith AV, Sparsø T,
Strawbridge RJ, Takeuchi F, Tan J, Trompet S, van den Akker E, van der Most PJ,
Verweij N, Vogel M, Wang H, Wang C, Wang N, Warren HR, Wen W, Wilsgaard T, Wong
A, Wood AR, Xie T, Zafarmand MH, Zhao JH, Zhao W, Amin N, Arzumanyan Z, Astrup
A, Bakker SJL, Baldassarre D, Beekman M, Bergman RN, Bertoni A, Blüher M,
Bonnycastle LL, Bornstein SR, Bowden DW, Cai Q, Campbell A, Campbell H, Chang
YC, de Geus EJC, Dehghan A, Du S, Eiriksdottir G, Farmaki AE, Frånberg M,
Fuchsberger C, Gao Y, Gjesing AP, Goel A, Han S, Hartman CA, Herder C, Hicks AA,
Hsieh CH, Hsueh WA, Ichihara S, Igase M, Ikram MA, Johnson WC, Jørgensen ME,
Joshi PK, Kalyani RR, Kandeel FR, Katsuya T, Khor CC, Kiess W, Kolcic I,
Kuulasmaa T, Kuusisto J, Läll K, Lam K, Lawlor DA, Lee NR, Lemaitre RN, Li H;
Lifelines Cohort Study, Lin SY, Lindström J, Linneberg A, Liu J, Lorenzo C,
Matsubara T, Matsuda F, Mingrone G, Mooijaart S, Moon S, Nabika T, Nadkarni GN,
Nadler JL, Nelis M, Neville MJ, Norris JM, Ohyagi Y, Peters A, Peyser PA,
Polasek O, Qi Q, Raven D, Reilly DF, Reiner A, Rivideneira F, Roll K, Rudan I,
Sabanayagam C, Sandow K, Sattar N, Schürmann A, Shi J, Stringham HM, Taylor KD,
Teslovich TM, Thuesen B, Timmers PRHJ, Tremoli E, Tsai MY, Uitterlinden A, van
Dam RM, van Heemst D, van Hylckama Vlieg A, van Vliet-Ostaptchouk JV,
Vangipurapu J, Vestergaard H, Wang T, Willems van Dijk K, Zemunik T, Abecasis
GR, Adair LS, Aguilar-Salinas CA, Alarcón-Riquelme ME, An P, Aviles-Santa L,
Becker DM, Beilin LJ, Bergmann S, Bisgaard H, Black C, Boehnke M, Boerwinkle E,
Böhm BO, Bønnelykke K, Boomsma DI, Bottinger EP, Buchanan TA, Canouil M,
Caulfield MJ, Chambers JC, Chasman DI, Chen YI, Cheng CY, Collins FS, Correa A,
Cucca F, de Silva HJ, Dedoussis G, Elmståhl S, Evans MK, Ferrannini E, Ferrucci
L, Florez JC, Franks PW, Frayling TM, Froguel P, Gigante B, Goodarzi MO, Gordon-
Larsen P, Grallert H, Grarup N, Grimsgaard S, Groop L, Gudnason V, Guo X,
Hamsten A, Hansen T, Hayward C, Heckbert SR, Horta BL, Huang W, Ingelsson E,
James PS, Jarvelin MR, Jonas JB, Jukema JW, Kaleebu P, Kaplan R, Kardia SLR,
Kato N, Keinanen-Kiukaanniemi SM, Kim BJ, Kivimaki M, Koistinen HA, Kooner JS,
Körner A, Kovacs P, Kuh D, Kumari M, Kutalik Z, Laakso M, Lakka TA, Launer LJ,
Leander K, Li H, Lin X, Lind L, Lindgren C, Liu S, Loos RJF, Magnusson PKE,
Mahajan A, Metspalu A, Mook-Kanamori DO, Mori TA, Munroe PB, Njølstad I,
O'Connell JR, Oldehinkel AJ, Ong KK, Padmanabhan S, Palmer CNA, Palmer ND,
Pedersen O, Pennell CE, Porteous DJ, Pramstaller PP, Province MA, Psaty BM, Qi
L, Raffel LJ, Rauramaa R, Redline S, Ridker PM, Rosendaal FR, Saaristo TE,
Sandhu M, Saramies J, Schneiderman N, Schwarz P, Scott LJ, Selvin E, Sever P,
Shu XO, Slagboom PE, Small KS, Smith BH, Snieder H, Sofer T, Sørensen TIA,
Spector TD, Stanton A, Steves CJ, Stumvoll M, Sun L, Tabara Y, Tai ES, Timpson
NJ, Tönjes A, Tuomilehto J, Tusie T, Uusitupa M, van der Harst P, van Duijn C,
Vitart V, Vollenweider P, Vrijkotte TGM, Wagenknecht LE, Walker M, Wang YX,
Wareham NJ, Watanabe RM, Watkins H, Wei WB, Wickremasinghe AR, Willemsen G,
Wilson JF, Wong TY, Wu JY, Xiang AH, Yanek LR, Yengo L, Yokota M, Zeggini E,
Zheng W, Zonderman AB, Rotter JI, Gloyn AL, McCarthy MI, Dupuis J, Meigs JB,
Scott RA, Prokopenko I, Leong A, Liu CT, Parker SCJ, Mohlke KL, Langenberg C,
Wheeler E, Morris AP, Barroso I; Meta-Analysis of Glucose and Insulin-related
Traits Consortium (MAGIC). The trans-ancestral genomic architecture of glycemic
traits. Nat Genet. 2021 Jun;53(6):840-860. doi: 10.1038/s41588-021-00852-9. Epub
2021 May 31. PMID: 34059833; PMCID: PMC7610958.

14: Schunk SJ, Kleber ME, März W, Pang S, Zewinger S, Triem S, Ege P, Reichert
MC, Krawczyk M, Weber SN, Jaumann I, Schmit D, Sarakpi T, Wagenpfeil S, Kramann
R, Boerwinkle E, Ballantyne CM, Grove ML, Tragante V, Pilbrow AP, Richards AM,
Cameron VA, Doughty RN, Dubé MP, Tardif JC, Feroz-Zada Y, Sun M, Liu C, Ko YA,
Quyyumi AA, Hartiala JA, Tang WHW, Hazen SL, Allayee H, McDonough CW, Gong Y,
Cooper-DeHoff RM, Johnson JA, Scholz M, Teren A, Burkhardt R, Martinsson A,
Smith JG, Wallentin L, James SK, Eriksson N, White H, Held C, Waterworth D,
Trompet S, Jukema JW, Ford I, Stott DJ, Sattar N, Cresci S, Spertus JA, Campbell
H, Tierling S, Walter J, Ampofo E, Niemeyer BA, Lipp P, Schunkert H, Böhm M,
Koenig W, Fliser D, Laufs U, Speer T; eQTLGen consortium; BIOS consortium.
Genetically determined NLRP3 inflammasome activation associates with systemic
inflammation and cardiovascular mortality. Eur Heart J. 2021 May
7;42(18):1742-1756. doi: 10.1093/eurheartj/ehab107. PMID: 33748830; PMCID:
PMC8244638.

15: Ahluwalia TS, Prins BP, Abdollahi M, Armstrong NJ, Aslibekyan S, Bain L,
Jefferis B, Baumert J, Beekman M, Ben-Shlomo Y, Bis JC, Mitchell BD, de Geus E,
Delgado GE, Marek D, Eriksson J, Kajantie E, Kanoni S, Kemp JP, Lu C, Marioni
RE, McLachlan S, Milaneschi Y, Nolte IM, Petrelis AM, Porcu E, Sabater-Lleal M,
Naderi E, Seppälä I, Shah T, Singhal G, Standl M, Teumer A, Thalamuthu A,
Thiering E, Trompet S, Ballantyne CM, Benjamin EJ, Casas JP, Toben C, Dedoussis
G, Deelen J, Durda P, Engmann J, Feitosa MF, Grallert H, Hammarstedt A, Harris
SE, Homuth G, Hottenga JJ, Jalkanen S, Jamshidi Y, Jawahar MC, Jess T, Kivimaki
M, Kleber ME, Lahti J, Liu Y, Marques-Vidal P, Mellström D, Mooijaart SP,
Müller-Nurasyid M, Penninx B, Revez JA, Rossing P, Räikkönen K, Sattar N,
Scharnagl H, Sennblad B, Silveira A, Pourcain BS, Timpson NJ, Trollor J; CHARGE
Inflammation Working Group, van Dongen J, Van Heemst D, Visvikis-Siest S,
Vollenweider P, Völker U, Waldenberger M, Willemsen G, Zabaneh D, Morris RW,
Arnett DK, Baune BT, Boomsma DI, Chang YC, Deary IJ, Deloukas P, Eriksson JG,
Evans DM, Ferreira MA, Gaunt T, Gudnason V, Hamsten A, Heinrich J, Hingorani A,
Humphries SE, Jukema JW, Koenig W, Kumari M, Kutalik Z, Lawlor DA, Lehtimäki T,
März W, Mather KA, Naitza S, Nauck M, Ohlsson C, Price JF, Raitakari O, Rice K,
Sachdev PS, Slagboom E, Sørensen TIA, Spector T, Stacey D, Stathopoulou MG,
Tanaka T, Wannamethee SG, Whincup P, Rotter JI, Dehghan A, Boerwinkle E, Psaty
BM, Snieder H, Alizadeh BZ. Genome-wide association study of circulating
interleukin 6 levels identifies novel loci. Hum Mol Genet. 2021 Apr
27;30(5):393-409. doi: 10.1093/hmg/ddab023. PMID: 33517400; PMCID: PMC8098112.

16: Hartiala JA, Han Y, Jia Q, Hilser JR, Huang P, Gukasyan J, Schwartzman WS,
Cai Z, Biswas S, Trégouët DA, Smith NL; INVENT Consortium; CHARGE Consortium
Hemostasis Working Group; GENIUS-CHD Consortium, Seldin M, Pan C, Mehrabian M,
Lusis AJ, Bazeley P, Sun YV, Liu C, Quyyumi AA, Scholz M, Thiery J, Delgado GE,
Kleber ME, März W, Howe LJ, Asselbergs FW, van Vugt M, Vlachojannis GJ, Patel
RS, Lyytikäinen LP, Kähönen M, Lehtimäki T, Nieminen TVM, Kuukasjärvi P,
Laurikka JO, Chang X, Heng CK, Jiang R, Kraus WE, Hauser ER, Ferguson JF, Reilly
MP, Ito K, Koyama S, Kamatani Y, Komuro I; Biobank Japan, Stolze LK, Romanoski
CE, Khan MD, Turner AW, Miller CL, Aherrahrou R, Civelek M, Ma L, Björkegren
JLM, Kumar SR, Tang WHW, Hazen SL, Allayee H. Genome-wide analysis identifies
novel susceptibility loci for myocardial infarction. Eur Heart J. 2021 Mar
1;42(9):919-933. doi: 10.1093/eurheartj/ehaa1040. PMID: 33532862; PMCID:
PMC7936531.

17: Lagou V, Mägi R, Hottenga JJ, Grallert H, Perry JRB, Bouatia-Naji N, Marullo
L, Rybin D, Jansen R, Min JL, Dimas AS, Ulrich A, Zudina L, Gådin JR, Jiang L,
Faggian A, Bonnefond A, Fadista J, Stathopoulou MG, Isaacs A, Willems SM,
Navarro P, Tanaka T, Jackson AU, Montasser ME, O'Connell JR, Bielak LF, Webster
RJ, Saxena R, Stafford JM, Pourcain BS, Timpson NJ, Salo P, Shin SY, Amin N,
Smith AV, Li G, Verweij N, Goel A, Ford I, Johnson PCD, Johnson T, Kapur K,
Thorleifsson G, Strawbridge RJ, Rasmussen-Torvik LJ, Esko T, Mihailov E, Fall T,
Fraser RM, Mahajan A, Kanoni S, Giedraitis V, Kleber ME, Silbernagel G, Meyer J,
Müller-Nurasyid M, Ganna A, Sarin AP, Yengo L, Shungin D, Luan J, Horikoshi M,
An P, Sanna S, Boettcher Y, Rayner NW, Nolte IM, Zemunik T, Iperen EV, Kovacs P,
Hastie ND, Wild SH, McLachlan S, Campbell S, Polasek O, Carlson O, Egan J, Kiess
W, Willemsen G, Kuusisto J, Laakso M, Dimitriou M, Hicks AA, Rauramaa R,
Bandinelli S, Thorand B, Liu Y, Miljkovic I, Lind L, Doney A, Perola M,
Hingorani A, Kivimaki M, Kumari M, Bennett AJ, Groves CJ, Herder C, Koistinen
HA, Kinnunen L, Faire U, Bakker SJL, Uusitupa M, Palmer CNA, Jukema JW, Sattar
N, Pouta A, Snieder H, Boerwinkle E, Pankow JS, Magnusson PK, Krus U, Scapoli C,
de Geus EJCN, Blüher M, Wolffenbuttel BHR, Province MA, Abecasis GR, Meigs JB,
Hovingh GK, Lindström J, Wilson JF, Wright AF, Dedoussis GV, Bornstein SR,
Schwarz PEH, Tönjes A, Winkelmann BR, Boehm BO, März W, Metspalu A, Price JF,
Deloukas P, Körner A, Lakka TA, Keinanen-Kiukaanniemi SM, Saaristo TE, Bergman
RN, Tuomilehto J, Wareham NJ, Langenberg C, Männistö S, Franks PW, Hayward C,
Vitart V, Kaprio J, Visvikis-Siest S, Balkau B, Altshuler D, Rudan I, Stumvoll
M, Campbell H, van Duijn CM, Gieger C, Illig T, Ferrucci L, Pedersen NL,
Pramstaller PP, Boehnke M, Frayling TM, Shuldiner AR, Peyser PA, Kardia SLR,
Palmer LJ, Penninx BW, Meneton P, Harris TB, Navis G, Harst PV, Smith GD,
Forouhi NG, Loos RJF, Salomaa V, Soranzo N, Boomsma DI, Groop L, Tuomi T, Hofman
A, Munroe PB, Gudnason V, Siscovick DS, Watkins H, Lecoeur C, Vollenweider P,
Franco-Cereceda A, Eriksson P, Jarvelin MR, Stefansson K, Hamsten A, Nicholson
G, Karpe F, Dermitzakis ET, Lindgren CM, McCarthy MI, Froguel P, Kaakinen MA,
Lyssenko V, Watanabe RM, Ingelsson E, Florez JC, Dupuis J, Barroso I, Morris AP,
Prokopenko I; Meta-Analyses of Glucose and Insulin-related traits Consortium
(MAGIC). Publisher Correction: Sex-dimorphic genetic effects and novel loci for
fasting glucose and insulin variability. Nat Commun. 2021 Feb 8;12(1):995. doi:
10.1038/s41467-021-21276-3. Erratum for: Nat Commun. 2021 Jan 5;12(1):24. PMID:
33558525; PMCID: PMC7870968.

18: Wallentin L, Eriksson N, Olszowka M, Grammer TB, Hagström E, Held C, Kleber
ME, Koenig W, März W, Stewart RAH, White HD, Åberg M, Siegbahn A. Plasma
proteins associated with cardiovascular death in patients with chronic coronary
heart disease: A retrospective study. PLoS Med. 2021 Jan 13;18(1):e1003513. doi:
10.1371/journal.pmed.1003513. PMID: 33439866; PMCID: PMC7817029.

19: Lagou V, Mägi R, Hottenga JJ, Grallert H, Perry JRB, Bouatia-Naji N, Marullo
L, Rybin D, Jansen R, Min JL, Dimas AS, Ulrich A, Zudina L, Gådin JR, Jiang L,
Faggian A, Bonnefond A, Fadista J, Stathopoulou MG, Isaacs A, Willems SM,
Navarro P, Tanaka T, Jackson AU, Montasser ME, O'Connell JR, Bielak LF, Webster
RJ, Saxena R, Stafford JM, Pourcain BS, Timpson NJ, Salo P, Shin SY, Amin N,
Smith AV, Li G, Verweij N, Goel A, Ford I, Johnson PCD, Johnson T, Kapur K,
Thorleifsson G, Strawbridge RJ, Rasmussen-Torvik LJ, Esko T, Mihailov E, Fall T,
Fraser RM, Mahajan A, Kanoni S, Giedraitis V, Kleber ME, Silbernagel G, Meyer J,
Müller-Nurasyid M, Ganna A, Sarin AP, Yengo L, Shungin D, Luan J, Horikoshi M,
An P, Sanna S, Boettcher Y, Rayner NW, Nolte IM, Zemunik T, Iperen EV, Kovacs P,
Hastie ND, Wild SH, McLachlan S, Campbell S, Polasek O, Carlson O, Egan J, Kiess
W, Willemsen G, Kuusisto J, Laakso M, Dimitriou M, Hicks AA, Rauramaa R,
Bandinelli S, Thorand B, Liu Y, Miljkovic I, Lind L, Doney A, Perola M,
Hingorani A, Kivimaki M, Kumari M, Bennett AJ, Groves CJ, Herder C, Koistinen
HA, Kinnunen L, Faire U, Bakker SJL, Uusitupa M, Palmer CNA, Jukema JW, Sattar
N, Pouta A, Snieder H, Boerwinkle E, Pankow JS, Magnusson PK, Krus U, Scapoli C,
de Geus EJCN, Blüher M, Wolffenbuttel BHR, Province MA, Abecasis GR, Meigs JB,
Hovingh GK, Lindström J, Wilson JF, Wright AF, Dedoussis GV, Bornstein SR,
Schwarz PEH, Tönjes A, Winkelmann BR, Boehm BO, März W, Metspalu A, Price JF,
Deloukas P, Körner A, Lakka TA, Keinanen-Kiukaanniemi SM, Saaristo TE, Bergman
RN, Tuomilehto J, Wareham NJ, Langenberg C, Männistö S, Franks PW, Hayward C,
Vitart V, Kaprio J, Visvikis-Siest S, Balkau B, Altshuler D, Rudan I, Stumvoll
M, Campbell H, van Duijn CM, Gieger C, Illig T, Ferrucci L, Pedersen NL,
Pramstaller PP, Boehnke M, Frayling TM, Shuldiner AR, Peyser PA, Kardia SLR,
Palmer LJ, Penninx BW, Meneton P, Harris TB, Navis G, Harst PV, Smith GD,
Forouhi NG, Loos RJF, Salomaa V, Soranzo N, Boomsma DI, Groop L, Tuomi T, Hofman
A, Munroe PB, Gudnason V, Siscovick DS, Watkins H, Lecoeur C, Vollenweider P,
Franco-Cereceda A, Eriksson P, Jarvelin MR, Stefansson K, Hamsten A, Nicholson
G, Karpe F, Dermitzakis ET, Lindgren CM, McCarthy MI, Froguel P, Kaakinen MA,
Lyssenko V, Watanabe RM, Ingelsson E, Florez JC, Dupuis J, Barroso I, Morris AP,
Prokopenko I; Meta-Analyses of Glucose and Insulin-related traits Consortium
(MAGIC). Sex-dimorphic genetic effects and novel loci for fasting glucose and
insulin variability. Nat Commun. 2021 Jan 5;12(1):24. doi:
10.1038/s41467-020-19366-9. Erratum in: Nat Commun. 2021 Feb 8;12(1):995. PMID:
33402679; PMCID: PMC7785747.
2020
1: van Zuydam NR, Ladenvall C, Voight BF, Strawbridge RJ, Fernandez-Tajes J,
Rayner NW, Robertson NR, Mahajan A, Vlachopoulou E, Goel A, Kleber ME, Nelson
CP, Kwee LC, Esko T, Mihailov E, Mägi R, Milani L, Fischer K, Kanoni S, Kumar J,
Song C, Hartiala JA, Pedersen NL, Perola M, Gieger C, Peters A, Qu L, Willems
SM, Doney ASF, Morris AD, Zheng Y, Sesti G, Hu FB, Qi L, Laakso M,
Thorsteinsdottir U, Grallert H, van Duijn C, Reilly MP, Ingelsson E, Deloukas P,
Kathiresan S, Metspalu A, Shah SH, Sinisalo J, Salomaa V, Hamsten A, Samani NJ,
März W, Hazen SL, Watkins H, Saleheen D, Morris AP, Colhoun HM, Groop L,
McCarthy MI, Palmer CNA; SUMMIT Steering Committee; CARDIOGRAMplusC4D Steering
Committee*. Genetic Predisposition to Coronary Artery Disease in Type 2 Diabetes
Mellitus. Circ Genom Precis Med. 2020 Dec;13(6):e002769. doi:
10.1161/CIRCGEN.119.002769. Epub 2020 Aug 13. PMID: 33321069; PMCID: PMC7748049.

2: Yazdani B, Kleber ME, Yücel G, Delgado GE, Benck U, Krüger B, März W, Krämer
BK. Association of double product and pulse pressure with cardiovascular and
all-cause mortality in the LURIC study. J Clin Hypertens (Greenwich). 2020
Dec;22(12):2332-2342. doi: 10.1111/jch.14067. Epub 2020 Oct 9. PMID: 33035393;
PMCID: PMC8030052.

3: Ritsch A, Duerr A, Kahler P, Hunjadi M, Stojakovic T, Silbernagel G,
Scharnagl H, Kleber ME, März W. Cholesterol Efflux Capacity and Cardiovascular
Disease: The Ludwigshafen Risk and Cardiovascular Health (LURIC) Study.
Biomedicines. 2020 Nov 21;8(11):524. doi: 10.3390/biomedicines8110524. PMID:
33233452; PMCID: PMC7700479.

4: Silbernagel G, Scharnagl H, Kleber ME, Hoffmann MM, Delgado G, Stojakovic T,
Gary T, Zeng L, Ritsch A, Zewinger S, Speer T, Schunkert H, Landmesser U, März
W, Grammer TB. Common APOC3 variants are associated with circulating ApoC-III
and VLDL cholesterol but not with total apolipoprotein B and coronary artery
disease. Atherosclerosis. 2020 Oct;311:84-90. doi:
10.1016/j.atherosclerosis.2020.08.017. Epub 2020 Sep 5. PMID: 32949947.

5: Delgado GE, Krämer BK, Scharnagl H, Fauler G, Stojakovic T, März W, Kleber
ME, Lammert A. Bile Acids in Patients with Uncontrolled Type 2 Diabetes Mellitus
- The Effect of Two Days of Oatmeal Treatment. Exp Clin Endocrinol Diabetes.
2020 Sep;128(9):624-630. doi: 10.1055/a-1069-7330. Epub 2020 Jan 2. PMID:
31896155.

6: Mahmoodi BK, Tragante V, Kleber ME, Holmes MV, Schmidt AF, McCubrey RO, Howe
LJ, Direk K, Allayee H, Baranova EV, Braund PS, Delgado GE, Eriksson N,
Gijsberts CM, Gong Y, Hartiala J, Heydarpour M, Pasterkamp G, Kotti S,
Kuukasjärvi P, Lenzini PA, Levin D, Lyytikäinen LP, Muehlschlegel JD, Nelson CP,
Nikus K, Pilbrow AP, Wilson Tang WH, van der Laan SW, van Setten J, Vilmundarson
RO, Deanfield J, Deloukas P, Dudbridge F, James S, Mordi IR, Teren A, Bergmeijer
TO, Body SC, Bots M, Burkhardt R, Cooper-DeHoff RM, Cresci S, Danchin N, Doughty
RN, Grobbee DE, Hagström E, Hazen SL, Held C, Hoefer IE, Hovingh GK, Johnson JA,
Kaczor MP, Kähönen M, Klungel OH, Laurikka JO, Lehtimäki T, Maitland-van der Zee
AH, McPherson R, Palmer CN, Kraaijeveld AO, Pepine CJ, Sanak M, Sattar N, Scholz
M, Simon T, Spertus JA, Stewart AFR, Szczeklik W, Thiery J, Visseren FLJ,
Waltenberger J, Richards AM, Lang CC, Cameron VA, Åkerblom A, Pare G, März W,
Samani NJ, Hingorani AD, Ten Berg JM, Wallentin L, Asselbergs FW, Patel RS.
Association of Factor V Leiden With Subsequent Atherothrombotic Events: A
GENIUS-CHD Study of Individual Participant Data. Circulation. 2020 Aug
11;142(6):546-555. doi: 10.1161/CIRCULATIONAHA.119.045526. Epub 2020 Jul 13.
PMID: 32654539; PMCID: PMC7493828.

7: Zheng Y, Huang T, Wang T, Mei Z, Sun Z, Zhang T, Ellervik C, Chai JF, Sim X,
van Dam RM, Tai ES, Koh WP, Dorajoo R, Saw SM, Sabanayagam C, Wong TY, Gupta P,
Rossing P, Ahluwalia TS, Vinding RK, Bisgaard H, Bønnelykke K, Wang Y, Graff M,
Voortman T, van Rooij FJA, Hofman A, van Heemst D, Noordam R, Estampador AC,
Varga TV, Enzenbach C, Scholz M, Thiery J, Burkhardt R, Orho-Melander M, Schulz
CA, Ericson U, Sonestedt E, Kubo M, Akiyama M, Zhou A, Kilpeläinen TO, Hansen T,
Kleber ME, Delgado G, McCarthy M, Lemaitre RN, Felix JF, Jaddoe VWV, Wu Y,
Mohlke KL, Lehtimäki T, Wang CA, Pennell CE, Schunkert H, Kessler T, Zeng L,
Willenborg C, Peters A, Lieb W, Grote V, Rzehak P, Koletzko B, Erdmann J, Munz
M, Wu T, He M, Yu C, Lecoeur C, Froguel P, Corella D, Moreno LA, Lai CQ,
Pitkänen N, Boreham CA, Ridker PM, Rosendaal FR, de Mutsert R, Power C,
Paternoster L, Sørensen TIA, Tjønneland A, Overvad K, Djousse L, Rivadeneira F,
Lee NR, Raitakari OT, Kähönen M, Viikari J, Langhendries JP, Escribano J,
Verduci E, Dedoussis G, König I, Balkau B, Coltell O, Dallongeville J,
Meirhaeghe A, Amouyel P, Gottrand F, Pahkala K, Niinikoski H, Hyppönen E, März
W, Mackey DA, Gruszfeld D, Tucker KL, Fumeron F, Estruch R, Ordovas JM, Arnett
DK, Mook-Kanamori DO, Mozaffarian D, Psaty BM, North KE, Chasman DI, Qi L.
Mendelian randomization analysis does not support causal associations of birth
weight with hypertension risk and blood pressure in adulthood. Eur J Epidemiol.
2020 Jul;35(7):685-697. doi: 10.1007/s10654-020-00638-z. Epub 2020 May 7. PMID:
32383070; PMCID: PMC7867117.

8: Pusceddu I, Herrmann W, Kleber ME, Scharnagl H, Hoffmann MM, Winklhofer-Roob
BM, März W, Herrmann M. Subclinical inflammation, telomere shortening,
homocysteine, vitamin B6, and mortality: the Ludwigshafen Risk and
Cardiovascular Health Study. Eur J Nutr. 2020 Jun;59(4):1399-1411. doi:
10.1007/s00394-019-01993-8. Epub 2019 May 25. PMID: 31129702; PMCID: PMC7230054.

9: Grammer TB, Dressel A, Gergei I, Kleber ME, Laufs U, Scharnagl H, Nixdorff U,
Klotsche J, Pieper L, Pittrow D, Silber S, Wittchen HU, März W. Author
Correction: Cardiovascular risk algorithms in primary care: Results from the
DETECT study. Sci Rep. 2020 Mar 31;10(1):5945. doi: 10.1038/s41598-020-59763-0.
Erratum for: Sci Rep. 2019 Jan 31;9(1):1101. PMID: 32231212; PMCID: PMC7105487.

10: Kleber ME, Delgado GE, März W. LDL receptor traffic: in the fast lane. Eur
Heart J. 2020 Mar 1;41(9):1054-1056. doi: 10.1093/eurheartj/ehz866. PMID:
31834377.

11: Kälsch AI, Scharnagl H, Kleber ME, Windpassinger C, Sattler W, Leipe J,
Krämer BK, März W, Malle E. Long- and short-term association of low-grade
systemic inflammation with cardiovascular mortality in the LURIC study. Clin Res
Cardiol. 2020 Mar;109(3):358-373. doi: 10.1007/s00392-019-01516-9. Epub 2019 Jul
1. PMID: 31263995.

12: Berger M, Kleber ME, Delgado GE, März W, Andreas M, Hellstern P, Marx N,
Schuett KA. Trimethylamine N-Oxide and Adenosine Diphosphate-Induced Platelet
Reactivity Are Independent Risk Factors for Cardiovascular and All-Cause
Mortality. Circ Res. 2020 Feb 28;126(5):660-662. doi:
10.1161/CIRCRESAHA.119.316214. Epub 2020 Jan 20. PMID: 31958034.

13: Shah S, Henry A, Roselli C, Lin H, Sveinbjörnsson G, Fatemifar G, Hedman ÅK,
Wilk JB, Morley MP, Chaffin MD, Helgadottir A, Verweij N, Dehghan A, Almgren P,
Andersson C, Aragam KG, Ärnlöv J, Backman JD, Biggs ML, Bloom HL, Brandimarto J,
Brown MR, Buckbinder L, Carey DJ, Chasman DI, Chen X, Chen X, Chung J, Chutkow
W, Cook JP, Delgado GE, Denaxas S, Doney AS, Dörr M, Dudley SC, Dunn ME,
Engström G, Esko T, Felix SB, Finan C, Ford I, Ghanbari M, Ghasemi S, Giedraitis
V, Giulianini F, Gottdiener JS, Gross S, Guðbjartsson DF, Gutmann R, Haggerty
CM, van der Harst P, Hyde CL, Ingelsson E, Jukema JW, Kavousi M, Khaw KT, Kleber
ME, Køber L, Koekemoer A, Langenberg C, Lind L, Lindgren CM, London B, Lotta LA,
Lovering RC, Luan J, Magnusson P, Mahajan A, Margulies KB, März W, Melander O,
Mordi IR, Morgan T, Morris AD, Morris AP, Morrison AC, Nagle MW, Nelson CP,
Niessner A, Niiranen T, O'Donoghue ML, Owens AT, Palmer CNA, Parry HM, Perola M,
Portilla-Fernandez E, Psaty BM; Regeneron Genetics Center, Rice KM, Ridker PM,
Romaine SPR, Rotter JI, Salo P, Salomaa V, van Setten J, Shalaby AA, Smelser DT,
Smith NL, Stender S, Stott DJ, Svensson P, Tammesoo ML, Taylor KD, Teder-Laving
M, Teumer A, Thorgeirsson G, Thorsteinsdottir U, Torp-Pedersen C, Trompet S, Tyl
B, Uitterlinden AG, Veluchamy A, Völker U, Voors AA, Wang X, Wareham NJ,
Waterworth D, Weeke PE, Weiss R, Wiggins KL, Xing H, Yerges-Armstrong LM, Yu B,
Zannad F, Zhao JH, Hemingway H, Samani NJ, McMurray JJV, Yang J, Visscher PM,
Newton-Cheh C, Malarstig A, Holm H, Lubitz SA, Sattar N, Holmes MV, Cappola TP,
Asselbergs FW, Hingorani AD, Kuchenbaecker K, Ellinor PT, Lang CC, Stefansson K,
Smith JG, Vasan RS, Swerdlow DI, Lumbers RT. Genome-wide association and
Mendelian randomisation analysis provide insights into the pathogenesis of heart
failure. Nat Commun. 2020 Jan 9;11(1):163. doi: 10.1038/s41467-019-13690-5.
PMID: 31919418; PMCID: PMC6952380.

14: Delgado GE, Krämer BK, Siekmeier R, Yazdani B, März W, Leipe J, Kleber ME.
Influence of smoking and smoking cessation on biomarkers of endothelial function
and their association with mortality. Atherosclerosis. 2020 Jan;292:52-59. doi:
10.1016/j.atherosclerosis.2019.11.017. Epub 2019 Nov 15. PMID: 31783198.

15: Moissl AP, Delgado GE, Krämer BK, März W, Kleber ME, Grammer TB. Area-based
socioeconomic status and mortality: the Ludwigshafen Risk and Cardiovascular
Health study. Clin Res Cardiol. 2020 Jan;109(1):103-114. doi:
10.1007/s00392-019-01494-y. Epub 2019 May 29. PMID: 31144063.